解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A bovine monoclonal antibody specific for bovine viral diarrhoea virus (BVDV) recognized all the reference strains of BVDV and over 90% of the field isolates tested. It neutralized the virus and precipitated a 56 k-58 k viral protein. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316756
更新日期:1991-01-01 00:00:00
abstract::The culture fluids of various anaerobic bacteria induced the synthesis of early antigens (EA) in Epstein-Barr virus (EBV) carrying lymphoblastoid cells. The culture fluids of Corynebacterium butyricum and Fusobacterium nucleatum were the effective inducer on EA. The inducing activity was, to some extent, dependent on ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310678
更新日期:1991-01-01 00:00:00
abstract::Two cell lines, CNS-5 and CNS-6, were established by cocultivation of sedimented cells in cerebrospinal fluid (CSF) from two anti-human T-lymphotropic virus type I (HTLV-I) antibody-positive male patients with encephalopathy and HTLV-I-associated myelopathy, respectively, with peripheral blood mononuclear cells from a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311306
更新日期:1991-01-01 00:00:00
abstract::Adenovirus type 7 vaccine strain was engineered to express foreign antigens from both the E3 early promoter in the E3 region and the major late promoter inserted between the E4 region and the right inverted terminal repeat. This multiple expression vector was used to express hepatitis B core antigen (HBcAg), hepatitis...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311300
更新日期:1991-01-01 00:00:00
abstract::Mutations were introduced by recombinant DNA techniques into 9 genes of an infectious molecular clone of human immunodeficiency virus type 1. The 24 mutants generated were characterized biochemically and biologically by transfection and infection experiments. None of the mutants which have mutations in gag (p17, p24, ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310491
更新日期:1991-01-01 00:00:00
abstract::Integration of bovine leukaemia virus DNA was investigated at all stages of infection in cattle. We report here the detection of integrated proviral DNA in the majority of antibody positive animals without lymphocytosis. In all but one case virus was integrated at a number of different sites. Hybridization analysis fa...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314319
更新日期:1991-01-01 00:00:00
abstract::The herpes simplex virus (HSV)-infected mouse model was used to correlate histopathological lesions in adrenal glands and ovaries with the localisation of viral nucleic acids and viral antigens, employing in situ hybridization and immunohistochemistry. In the adrenals, the lesions were mainly restricted to the zona fa...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310768
更新日期:1991-01-01 00:00:00
abstract::The viral erythrocytic infection (VEI) of sea bass (Dicentrarchus labrax) is evidenced by the presence of inclusion bodies in the erythrocytes and erythroblasts. Virus-like particles (VEIV) about 135-150 nm in diameter were observed in erythroblasts of affected fish. No culturable virus could be recovered from the org...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310951
更新日期:1991-01-01 00:00:00
abstract::Twenty-eight Belgian field isolates of bovine herpesvirus 4 (BHV-4) coming from a variety of clinical diseases have been studied by restriction analysis and Southern blot hybridization. The unique central part of the genome was very well conserved among strains; only one variation in a restriction site was detected in...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01319227
更新日期:1991-01-01 00:00:00
abstract::Five cDNA probes prepared from molecular clones representing genomic RNA sequences of the virulent Miller strain of transmissible gastroenteritis virus (TGEV) were used in a dot blot hybridization assay to detect TGEV in cell culture and fecal specimens. Two clones (pA2 and pB4) represent nucleotide base pairs at the ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01319234
更新日期:1991-01-01 00:00:00
abstract::The adsorption and retention properties of native (unfixed) and glutaraldehyde-fixed alfalfa mosaic virus (AMV) antigens to the polystyrene of ELISA plates were studied using [35S]-labelled virus preparations. It was shown that adsorption was a temperature-dependent, relatively slow process which varied between differ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310767
更新日期:1991-01-01 00:00:00
abstract::Blot hybridization analysis of infected bovine herpesvirus 1 (BHV-1) cellular RNA isolated at various times post infection and after treatment with specific metabolic inhibitors was used to characterize transcription of the BHV-1 Cooper isolate. Synthesis of BHV-1 RNA was detected as early as 3 h post infection and re...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316744
更新日期:1991-01-01 00:00:00
abstract::Attenuated, gene-deletion mutants of pseudorabies virus (PRV) were tested for their ability to establish a reactivatable latent infection in pigs. The viruses (designated A, B, and C) were from each of three vaccines commercially available in the United States. Viruses A and C were similar in that they had genetically...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310949
更新日期:1991-01-01 00:00:00
abstract::During the epidemic outbreak in the region of Greifswald in the winter 1974/75, we found influenza virus variants which showed differences in the electrophoretic mobility of HA. Among the 25 isolates 13 were of slower and 12 of higher mobility. HA1 of 6 isolates was studied by determining the number of the carbohydrat...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310484
更新日期:1991-01-01 00:00:00
abstract::Receptor-mediated activation is accompanied by phospholipid metabolism and by calcium fluctuation resulting in a chemiluminescence (CL) response in the neutrophil. This pathway involves activation of protein kinase C (PKC) and the NADPH oxidase. Artificial stimulants such as phorbol esters, specifically 12-O-tetradeca...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310506
更新日期:1990-01-01 00:00:00
abstract::This study examines viral protein and DNA synthesis in Spodoptera frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV) infections of S. frugiperda and Trichoplusia ni cells. A total of 28 infected cell specific polypeptides (ICSPs) were detected in the productive S. frugiperda cells. Of these, 14 were identified...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310626
更新日期:1990-01-01 00:00:00
abstract::Strains of an influenza H10N4 virus have been isolated during an outbreak of a respiratory disease in mink on the south-east coast of Sweden. This was the first example of a disease in mammals caused by the H10 subtype. We compared the A/mink/Sweden/84 strain with two recent avian H10N4 isolates, one from fowl and ano...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01318353
更新日期:1990-01-01 00:00:00
abstract::The effects of human alpha-, beta-, or gamma-interferon (IFN) on the replication and production of human T-lymphotrophic virus type-I (HTLV-I) were investigated in a human T-cell line, MT-2. Virus transmission and production estimated by syncytium formation and HTLV-I-associated reverse transcriptase (RT) activity wer...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310623
更新日期:1990-01-01 00:00:00
abstract::Swine testicle cell lines were established by transformation of primary swine testicle (PST) cells with an SV40 plasmid (pSV3-neo), which contains genes conferring resistance to neomycin and expressing SV40 large T antigen. Plasmid DNA was transfected into PST cells using a lipofection system. Two related plasmids, pS...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310532
更新日期:1990-01-01 00:00:00
abstract::IG 1, a temperate phage of Bacillus subtilis, is strongly induced from its lysogens by 6-(p-hydroxyphenylazo)-uracil, an azopyrimidine known as selectively inhibiting the B. subtilis DNA polymerase III. IG 1 phages originated either by induction or infection multiply, abundantly, in the presence of that azopyrimidine,...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316671
更新日期:1990-01-01 00:00:00
abstract::Antibody-like molecules consisting of the human CD 4 extracellular domain fused to human IgG1 heavy chain constant regions were genetically constructed and expressed in a BHK cell stable transfectant. Purified chimeric antibodies bound to HIV particles as it was shown by immuno electron microscopy, inhibited fusions o...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310503
更新日期:1990-01-01 00:00:00
abstract::Three ponies were inoculated with plasma containing 10(4.8) TCID50 of equine infectious anemia virus (EIAV) and observed for 165 to 440 days. Each pony developed a febrile response within 3 weeks of infection during which a plasma viremia greater than or equal to 10(3.5) TCID50/ml was observed. Analyses of four isolat...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311054
更新日期:1990-01-01 00:00:00
abstract::3Y1 rat fibroblasts transformed by adenovirus type 12 or by its E1A gene formed syncytia when cocultivated with the Friend as well as other ecotropic murine leukemia-virus-producing cells. In contrast, the parental 3Y1 cells and those transformed by other tumor viruses or by a chemical carcinogen exhibited no syncytiu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310628
更新日期:1990-01-01 00:00:00
abstract::Exposure of human lung fibroblasts to human cytomegalovirus (HCMV) stimulated a rapid increase in the release of [3H] from cells prelabelled with radiolabelled arachidonic acid ([3H]AA). Maximum stimulation of [3H] release was observed at 20 min postinfection and was quantitatively similar to that induced by the tumor...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316678
更新日期:1990-01-01 00:00:00
abstract::The nucleo-, phospho- and matrix protein of measles virus were localized at high resolution within infected cells by use of post-embedding immunogold labelling techniques. In general, labelling with monospecific antibodies as well as with a polyvalent rabbit anti-measles hyperimmune antiserum revealed measles virus po...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311011
更新日期:1990-01-01 00:00:00
abstract::Agarose in situ digestion was used to prepare intact Amsacta moorei entomopoxvirus (AmEPV) DNA from embedded occlusion bodies (OBs). Direct dissolution of OBs in agarose eliminated the necessity for separate purification of virions. A physical map of AmEPV DNA was constructed for five restriction enzymes (BamHI, EcoRI...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310704
更新日期:1990-01-01 00:00:00
abstract::Purified DNA from 45 isolates of suis herpes virus 1 (SHV1) collected between 1980 and 1987 from clinical outbreaks of Aujeszky's disease on French farms was compared by restriction fragment pattern (RFP) analysis. The BamHI generated RFPs were found to be distinguishable, confirming RFP analysis as a potential epidem...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01323161
更新日期:1990-01-01 00:00:00
abstract::The complete nucleotide sequence of genome segment S9, which was reported as the ninth largest among the 12 genome segments of rice dwarf virus, was determined. The segment was 1,305 bp long and coded for a protein composed of 351 amino acids (Mr 38,930). The terminal sequences of the segment were found to consist of ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313885
更新日期:1989-01-01 00:00:00
abstract::Two subgroup-specific monoclonal antibodies (MAb) raised in mice against group A human rotavirus were shown to react by immunoblotting with the trimeric form of VP6 of the homologous subgroup and successfully applied to development of new single-sandwich ELISA systems for rapid subgrouping of human strains. All of the...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317927
更新日期:1989-01-01 00:00:00
abstract::Serological and genetical relationships of three salmonid herpesviruses [strain H-83, OO-7812 strain of Oncorhynchus masou virus (OMV) and Herpesvirus salmonis] were investigated. Although the serological relationships of these viruses were not distinctly demonstrated by cross-neutralization test, cross enzyme-linked ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313818
更新日期:1989-01-01 00:00:00
abstract::Virus-like particles (VLP), morphologically similar to togavirus particles, were detected in the sera of chimpanzees and humans with chronic non-A, non-B (NANB) hepatitis. Particles resembling the virus were also found in the cytoplasm of hepatocytes obtained from NANB hepatitis infected chimpanzees. Furthermore, two ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315557
更新日期:1989-01-01 00:00:00
abstract::The stability of regions containing tandemly reiterated sequences in the S component of the herpes simplex virus type 1 (HSV-1) genome was determined, by comparing restriction fragments of the regions among sets of HSV-1 isolates derived from a single source. The 6 reiterations examined were grouped into three. Reiter...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313958
更新日期:1989-01-01 00:00:00
abstract::R 61,837, a new antirhinovirus compound, was able to protect several susceptible rhinoviruses against inactivation by mild acidification or heat. This observation strengthens the hypothesis that the drug exerts antiviral activity by a direct interaction with the viral protein capsid to stabilize the particle. However,...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311037
更新日期:1989-01-01 00:00:00
abstract::Antisera from dengue patients and dengue virus infected rabbits recognized octapeptides corresponding to linear amino acid sequences in the envelope protein of dengue 2 (Jamaica 1409). Although no peptide was recognized by sera from all dengue infected hosts, two peptides (216LPLPWLPG223 and 448FSGVSWTM455) were recog...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311358
更新日期:1989-01-01 00:00:00
abstract::Interleukin-2 dependent feline T-lymphoblastoid cells designated as MYA-1 cells were established. The cells were free from exogenous retroviruses and sensitive for replication of feline immunodeficiency virus (FIV). FIV can grow more efficiently in MYA-1 cells than in feline primary peripheral blood mononuclear cells....
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313750
更新日期:1989-01-01 00:00:00
abstract::The pathogenicity of 5 different encephalomyocarditis (EMC) virus isolates was investigated in swine fetuses following injection of each virus in utero. Laparotomies were performed on 3 pregnant sows in early mid-third (39-40 days) of gestation and on 5 sows in the late mid-third (70-72 days) of gestation, and groups ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310517
更新日期:1989-01-01 00:00:00
abstract::We have applied an RNA:RNA hybridization test for the detection of human coronavirus 229E. This test is undergoing further development but already allows a diagnosis of HCV 229E infection within 48 hours. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315554
更新日期:1989-01-01 00:00:00
abstract::The amount of viroid RNA required for sequence analysis can be reduced by five to six orders of magnitude when a modified "polymerase chain reaction" (PCR) is used for the amplification of the reversely transcribed, overlapping viroid cDNAs. By applying this procedure it is possible to establish the molecular structur...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313962
更新日期:1989-01-01 00:00:00
abstract::The sequence of the gene encoding the membrane protein of human coronavirus 229 E (HCV 229 E) has been determined. The primary translation product, deduced from the DNA sequence, is a polypeptide of 225 amino acids with a predicted molecular weight of 26,000. The polypeptide has 3 potential N-glycosylation sites. Many...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317928
更新日期:1989-01-01 00:00:00
abstract::Synthesis of the Epstein-Barr virus (EBV) associated early antigen (EA) can be induced by a variety of agents in Raji cells, a latently EBV-infected Burkitt lymphoma line. We investigated the role of lipoproteins in this EA induction system. Cell growth was not affected by lipoprotein-deficiency, but EA induction by m...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313877
更新日期:1989-01-01 00:00:00